In cryptography, an initialization vector (IV) or starting variable (SV) is an input to a cryptographic primitive being used to provide the initial state. The IV is typically required to be random or pseudorandom, but sometimes an IV only needs to be unpredictable or unique. Randomization is crucial for some encryption schemes to achieve semantic security, a property whereby repeated usage of the scheme under the same key does not allow an attacker to infer relationships between (potentially similar) segments of the encrypted message. For block ciphers, the use of an IV is described by the modes of operation.

Some cryptographic primitives require the IV only to be non-repeating, and the required randomness is derived internally. In this case, the IV is commonly called a nonce (a number used only once), and the primitives (e.g. CBC) are considered stateful rather than randomized. This is because an IV need not be explicitly forwarded to a recipient but may be derived from a common state updated at both sender and receiver side. (In practice, a short nonce is still transmitted along with the message to consider message loss.) An example of stateful encryption schemes is the counter mode of operation, which has a sequence number for a nonce.

The IV size depends on the cryptographic primitive used; for block ciphers it is generally the cipher's block-size. In encryption schemes, the unpredictable part of the IV has at best the same size as the key to compensate for time/memory/data tradeoff attacks. When the IV is chosen at random, the probability of collisions due to the birthday problem must be taken into account. Traditional stream ciphers such as RC4 do not support an explicit IV as input, and a custom solution for incorporating an IV into the cipher's key or internal state is needed. Some designs realized in practice are known to be insecure; the WEP protocol is a notable example, and is prone to related-IV attacks.